The objective of the study was to evaluate the influence of moisture content of bakery feed supplementary on using, honey yield, larval rearing capacity of exotic bees (Apis mellifera) as well as the quality change of forage cake during the feeding process and base on it to choose the best cake moisture. The feed used in the experiment was the studied formula that was caked with 5 different moisture contents (14%, 16%, 18%, 20%, 22%). The experiment was carried out at the bee farm of the Bee Research Center in Tat Thang commune, Thanh Son district, Phu Tho from May 2021 to September 2021. Research results show that by 5 different moisture levels in the produced feed cake (14%, 16%, 18%, 20%, 22%), the food cake with 20% moisture content was the most suitable for feed production, giving the highest honey yield, 20.26 kg/herd during the experimental period of acacia molasses crop (the difference was statistically significant at the level of P < 0.05). The analysis results of the moisture content of the feed cake when fed to the bees with different moisture levels were observed for 11 days and showed that under the influence of temperature and humidity in the flock caused the moisture content of the forage cake to increase from day 1 to day 7 and decrease gradually after the remaining days. The results of analysis of total residues, fungi (yeast, mold) and aflatoxin toxins of the feed cake showed that no toxins were detected in the feed samples, the bees were using. During using, the total number of fungi (yeast, mold) was increased from 103cfu/g to 105cfu/g.