Research on the growth potential of three crossbreeds between Charolais, Red Angus and Droughtmaster bulls with Brahman crossbred female from birth to 21st month of age reared in Hanoi, Hung Yen and Thai Nguyen. The results of monitoring 60 crossbred cows (20 heads/crossbred) showed that the average weight of the Charolais and Red Angus combination was higher than that of the Droughtmaster cross (P<0.05) at the age milestones from birth to birth 21st month of age. At 21st month of age, the weight of the Charolais × Brahman crossbred female combination was the highest (478.9 kg), followed by the Red Angus × Brahman Brahman crossbred female combination (451.2 kg) and the lowest was the Droughtmaster × Brahman crossbred female combination (410.7 kg). The ability to increase weight of crossbred cows from birth to 21st month of age of the Charolais and Red Angus crosses was higher than that of the Droughtmaster combination (P<0.05) respectively reaching 710.9; 669.5 and 608.1 g/head/day.