The experiment was conducted at beef cattle households in Ben Cat town, Binh Duong province to evaluate effect of cattle manure management and treatment on CH4, NH3, CO2 and H2S emissions in cattle barn. The experiment was arranged in a randomized group design, with two treatments (Control and experimental treatment), in each treatment 5 Lai Sind cattles (3 breeding cows and 2 calves) per experimental unit were applied with 9 replicates. In which, the cows were the same in terms of body weight, age, number of parities and last calving date, the calves were the same in terms of sex ratio (1 male and 1 female / experimental unit), age and body weight in 2 treatments; Feeding method and diet in 2 treatments were the same. The results show that concentration of CH4, CO2, NH3 and H2S inside and outside of the barn in the experimental group were in ranged of TCVN (TCVN 5938-1995) and QCVN (QCVN 01-79: 2011), but in the control group they were exceeded, specifically: Concentration of CH4, CO2, NH3 and H2S inside the barn in tlhe control treatment was higher than that in the experimental treatment 4.0; 2.3; 1.8 and 6.4 times respectively. Similarly, the gas concentration outside the barn in the control group was higher than that in the experimental group 7.6; 6.9; 3.2 and 15.0 times respectively. Time of mating after calving of cows decreased by 11.1 days comparing to control group, weight gain of 2-12 months- old calves was 449.0 g / head / day, higher than in the control group 5.57%. The rate of cases and number of days of animal having gastrointestinal and respiratory disease in experimental group decreased comparing to the control group.