The study aimed to assess the prevalence of parasitic skin diseases and evaluate treatment efficacy in dogs and cats at the Animal Rescue Station and Community Veterinary Clinic, University of Agriculture and Forestry, Thai Nguyen University. The study was conducted on 338 dogs and 93 cats rescued at the station and coming to the hospital for examination and treatment, divided by age, season, gender and coat type. The result is shown: Dogs under 1 year old showed the highest infection rate (40.18%), followed by those over 2 years (33.67%), with the lowest in the 1–2 year group (24.22%). In cats, infection was highest in those over 2 years (37.50%), followed by those under 1 year (36.84%), and lowest in the 1–2 year group (16.13%). Seasonally, the highest infection rates were in spring (dogs 53.42%, cats 50%), followed by summer, winter, and lowest in autumn. Gender had no significant effect. Hair coat type influenced infection rates: hairless animals had the lowest rates, followed by short-haired, long-haired, and the highest in curly-haired dogs (60.49%) and cats (100%). Treatment regimens showed high efficacy, with cure rates ranging from 88.89% to 100%.