A total of 35 sows in litter of 2-6 were used to test the effect of supplement nano mineral in different level on the reproductive performance in period of 140 days. The experiment was conducted on foreign pig farms of Ha Thai Production and Trading Joint Stock Company, Pho Yen town, Thai Nguyen province from March to August 2019. The experiment was design by one factor complete random design. Sows was allocated randomly in 5 treatments, each treatment had 7 sows, each sow was a replicate. Sows in control group were fed inorganic mineral recommended by NRC, 2012 (25 mg Mn, 80 mg Fe, 20 mg Cu, 0.15 mg Co, 0.15 mg Se and 100 mg Zn/kg feed) while sows in treatments groups were fed nano mineral with different levels of Mn, Fe, Cu, Se, Co and Fe including (10; 32; 8; 0,06; 0,06 và 40 mg); (15; 48; 12; 0,09; 0,09 và 60 mg); (20; 64; 16; 0,12; 0,12 và 80 mg); (25; 80; 20; 0,15; 0,15 và 100 mg) respectively. The result showed that (i) supplement of nano mineral reduced the mineral content in blood and live of suckling piglets compare with inorganic mineral supplement differents level of mineal in nano or inorganic form had significant impact on mineral content in blood and liver of suckling piglets (P<0.05); (ii) There were no significant differences in parameters of reproductive performance between treatments; (iii) Using nano mineral with level of 40% of NRC, 2012 recommendation still meet the mineral requirement and did not impact on reproductive performance of sows.